Research Based Professional Formulas

 

 

 

 

 

 



C-NAG 90s

Brain Boost


Phosphatidylserine
+ DHA (Algal Oil)

 

60 & 120 Vegan Soft Caps

NPN 80071505

view label

 

 

NUTRIENT 1 Vegan Soft Cap contains DAILY DOSE
(2 Vegan Soft Caps)
Algal Oil 40% DHA
Schizochytrium aggregatum
300 mg 600 mg
Phosphatidylserine (PS)
(from 177 mg - 85% PS complex)
150 mg 300 mg

 

Recommended dose:

Adults: Take 2 capsules daily in divided doses, or as directed by a health care practitioner.

Recommended use or purpose:

Cautions and warnings:

 

Brain Boost combines two essential brain nutrients: Phosphatidylserine (PS) and Docosahexaenoic Acid (DHA), at clinically established amounts to provide the most effective cognitive function improvement formula available.

Phosphatidylserine (PS)

Vitex’s Brain Boost capsules provide plant-derived (Non-GMO soybean oil) phospholipids supplying 150 mg of phosphatidylserine (PS) from 177 mg of 85% pure PS complex, the purest form yet developed.

In May, 2003 the US Food and Drug Administration gave "qualified health claim" status to phosphatidylserine thus allowing labels to state "consumption of phosphatidylserine may reduce the risk of dementia and cognitive dysfunction in the elderly" along with the disclaimer "very limited and preliminary scientific research suggests that phosphatidylserine may reduce the risk of cognitive dysfunction in the elderly.

Phosphatidylserine (PS) is produced in the brain but ageing slows the production of PS to sub-optimal levels that preclude us from functioning at full mental capacity. A growing body of scientific findings supports that supplementation with PS plays a vital role in improving and reversing the damage that age and/or disease has set in motion.

PS is a phospholipid that is found in all cells, but is most highly concentrated in the walls (membranes) of brain cells, making up about 70% of its nerve tissue mass. There it aids in the storage, release and activity of many vital neurotransmitters and their receptors. PS also aids in cell-to-cell communication.

PS is involved in the upkeep and restoration of nerve cell membranes. Among its list of functions:

Research has shown that dietary supplementation with PS can slow and even reverse the decline of learning, mood, memory, concentration, word recall related to dementia or age-related cognitive impairment in middle-aged and elderly subjects.

Age-related cognitive decline

Left to its own devices, the brain will succumb to the insults of age, starting by about the fourth or fifth decade of life. Putting your finger on a name, face, car keys, a phone number or a word, can become increasingly challenging and annoying with each passing decade. The net result of mental ageing is cognitive decline, including a gradual loss of the ability to learn, reason, concentrate and remember - basically, a decrease in the higher brain functions. But, as scientists are discovering, PS can help prime the brain back to a more youthful level of activity.

U.S. scientists at the Memory Assessment Clinics in Bethesda, MD, found that, compared to placebo, a 12-week daily regimen of PS (300 milligrams daily) improved learning and memory related to daily living, such as the ability to learn and recall names, faces and numbers. These effects seemed to last beyond the study period. In terms of name-face recognition, the authors report that the subgroup improved to a point that their brains returned to a much younger cognitive age, resembling the mind of a 52-year-old rather than someone who is 64.

In a large, multicenter study of geriatric patients (494 patients, aged 65 to 93 years), from 23 geriatric or general medicine units with moderate to severe age-related cognitive decline, those who received PS treatment (300 milligrams per day for six months) showed significantly improved behavior, such as increased motivation, initiative and socialization, compared to the placebo group. Patients were examined just before starting therapy, and three and six months thereafter. The authors suggest that, "These results are clinically important since the patients were representative of the geriatric population commonly met in clinical practice."

 

Docosahexaenoic Acid (DHA)

Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability, whereas deficiencies of DHA are associated with deficits in learning. DHA is taken up by the brain in preference to other fatty acids. The turnover of DHA in the brain is very fast, more so than is generally realized.

Decreases in DHA in the brain are associated with cognitive decline during ageing and with onset of sporadic Alzheimer disease. The leading cause of death in western nations is cardiovascular disease. Epidemiological studies have shown a strong correlation between fish consumption and reduction in sudden death from myocardial infarction. The reduction is approximately 50% with 200 mg day of DHA from fish.

DHA is the most active component in fish. Not only does fish oil reduce triglycerides in the blood and decrease thrombosis, but it also prevents cardiac arrhythmias. The association of DHA deficiency with depression is the reason for the robust positive correlation between depression and myocardial infarction.

DHA is present in algae (Schizochytrium aggregatum), fatty fish (salmon, tuna, mackerel), and mother's milk. DHA is present at low levels in meat and eggs, but is not usually present in infant formulas. EPA is also present in fatty fish. Alpha-linolenic acid, (ALA) provided in vegetable oils such as flax seed oil and hemp seed oil is poorly converted to DHA in man (< 0.1% conversion efficiency).

DHA decreases the proliferation of tumor cells, whereas excess arachidonic acid (AA) a long chain n-6 fatty acid increases their proliferation. These opposite effects are also seen with inflammation, particularly with rheumatoid arthritis and with asthma.

DHA has a positive effect on diseases such as hypertension, arthritis, atherosclerosis, depression, adult onset diabetes mellitus, myocardial infarction, thrombosis, and some cancers.

Alpha Linolenic Acid (ALA) does not increase plasma DHA in humans (< 0.1% conversion efficiency in humans). In fact, neither ALA nor EPA is an effective source of DHA due to minimal in vivo production of DHA from these precursors in humans, indicating that preformed DHA is most effective in maintaining sufficient tissue stores.

Schizochytrium aggregatum (DHA)

Schizochytrium aggregatum is a genus of unicellular protists, one of several that make up the thraustochytrids. These organisms were once thought of as a kind of fungus, but are now assigned to the stramenopiles, a group that also contains kelp and an array of micro-algae. Members of the genus produce significant amounts of DHA and are grown commercially as a source DHA for nutrition supplementation.

This algal source of DHA is a recently available high concentration source of DHA without the potential risk of contamination from heavy metals or toxins which can come from fish sources of EPA/DHA and is a preferred source as it conserves fish stocks and helps preserve the delicate balance of marine aqua culture.

NOTE: Brain Boost contains 120 mg of the biologically active DHA per 450 mg capsule; which compares to the standard 18:12 fish oil capsules which contain 120 mg of DHA per 1,000 mg capsule.

NOTE: For maximum benefit, take the SOURCE Optimum, SONA based vitamin/mineral/ enzyme formula and VEGAN Omega 3-6-9 to provide the body with optimum levels of other essential nutrients necessary to help maintain long term good health.

Packaging: Packed in light & oxygen resistant recyclable PETE (Bisphenol A free) bottles. 
Gluten Free: Contains no artificial preservatives, colours, flavours, starch, sugar, lactose, dairy, salt, yeast or wheat.
Vegan Capsule Shell: Non-GMO modified cassava starch (tapioca), purified water, vegetable glycerin


 

Research:

Docosahexaenoic Acid and Adult Memory: A Systematic Review and Meta-Analysis
More benefits emerging for one type of omega-3 fatty acid: DHA
The role of docosahexaenoic and the marine food web as determinants of evolution and hominid brain development: The challenge for human sustainability
EPA Stands Alone as a Depression Fighter
Omega-3 may minimise damaging effects of junk food on brain: Research review
Omega-3 and vitamin D may help clear Alzheimer's plaques
Omega-3 rich diet can boost children’s IQ, says meta-analysis
Omega-3 backed for postpartum depression
Omega-3 supplementation backed for depression in elderly
Vitamin E shows cognitive function benefits: Study
Marine Omega-3s May Boost Heart Health
Omega-3 Again Linked to Lower Inflammation: Study
Men May Benefit from Omega-3 More than Women: Study
Omega-3 linked to better memory in former depressives: Study
Omega-3 linked to lower heart arrhythmic risk
Omega-3s may improve health of blood vessels: Meta-analysis
Omega-3 rich diet could protect against brain aging: Study
DHA omega-3 linked to improved literacy for ADHD children: Study
Omega-3, -6 combination shows promise for inattention and cooperation in ADHD kids

List of articles for more information.

https://examine.com/supplements/phosphatidylserine/

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